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As Table shows all guidelines recommend OACs
2019-05-23
As Table 2 shows, all guidelines recommend OACs for patients with a CHADS2 score of ≥2, whereas recommendations for low-risk patients with a CHADS2 score of 0/1 differ slightly across guidelines. Evidence indicating that novel OACs decrease the risk of ICH by half as compared with warfarin has affec
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br Future directions There is increasing
2019-05-23
Future directions There is increasing evidence that osteoblasts are important components of the bone metastatic niche, but their precise contribution in supporting tumour cell engraftment, dormancy and survival remains to be defined. Unlike osteoclasts, the role of osteoblasts in bone metastasis
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La cr tica realizada al ccpor las diferentes comisiones deve
2019-05-23
La crítica realizada al ccpor las diferentes comisiones develó la verticalidad en la toma de decisiones políticas, las cuales se agudizaban cuando se realizaban acciones militares, lo que ocasionó constantes fricciones y sanciones D-Luciferin Supplier algunos miembros de la Comisión Militar o de las
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Na defini o da Secretaria Nacional
2019-05-23
Na definição da Secretaria Nacional de Políticas de Promoção da Igualdade Racial, vinculada atualmente ao Ministério dos Direitos Humanos do governo federal, as ações afirmativas são políticas públicas que têm como objetivo order TAK-242 correção de desigualdades raciais acumuladas ao longo dos anos
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After a decade of political and economic crisis between
2019-05-23
After a decade of political and economic crisis between 1999 and 2010, health education in Zimbabwe was in a desperate state and required a major overhaul. UZCHS reported a 60% decrease in medical student enrolment, a 61% faculty vacancy rate, a 50% increase in failure rate, and the specialist train
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br In the past year
2019-05-23
In the past year, migration to Europe from Africa and the Middle East has reached unprecedented levels. In 2016, 181 405 migrants reached the shores of Italy and more than 5000 died trying to reach the southern coasts of Europe. Many migrants seek to escape war, poverty, persecution, or ill treatm
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br Discussion This observation reports an unusual associatio
2019-05-22
Discussion This observation reports an unusual association of LEMS with LGL leukemia occurring in the same patient, and clearly shows that both diseases benefited from LGL leukemia therapy. Methotrexate and steroids rapidly induced hematological complete remission associated with disappearance of
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br Cardiac imaging br Head up
2019-05-22
Cardiac imaging Head-up tilt testing Head-up tilt (HUT) testing is recommended to judge an episode of syncope to be likely caused by VF by excluding neurally mediated syncope (NMS). However, NMS may coexist with Brugada syndrome [42]. We conducted HUT testing in 46 patients with type-1 Brugada
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br Interpretation of identified genetic variants and genetic
2019-05-22
Interpretation of identified genetic variants and genetic counseling Although the current expert consensus statement recommends that comprehensive or BrS1 (SCN5A) targeted BrS genetic testing can be useful for genetic testing [63], not all the published SCN5A mutations in BrS have been subjected
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The outcome of sinus node modification with
2019-05-22
The outcome of sinus node modification with radiofrequency ablation has been reported, but it involves a high invasive risk associated with the ablation. Thus, careful confirmation of the earliest activation site and ablation of that site is important [2,3]. The clinical use of the 3D-mapping system
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MM-102 cost We describe a novel case wherein
2019-05-22
We describe a novel case, wherein a patient with AML with inv (16) underwent allogeneic bone marrow transplantation from a related sibling donor which contained a small subpopulation of premalignant stem MM-102 cost with trisomy 11. Fourteen years following transplantation, this patient presented w
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In an earlier study we used a
2019-05-22
In an earlier study, we used a questionnaire to assess musculoskeletal pain in patients with CML who had achieved DMR (MR4.0) and discontinued TKI treatment, including IM, nilotinib, and dasatinib [5]. Nine out of the 27 patients surveyed developed musculoskeletal pain after discontinuing TKIs. In t
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The study reported high rates of
2019-05-21
The study reported high rates of antimicrobial resistance and also reminds us of the paucity of new drugs to treat such infections, especially in neonates, as well as the paucity of data on antimicrobial pharmacokinetics in this population. Observational and interventional multicentre studies are ne
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Algunos cambios sin embargo estaban llegando para
2019-05-21
Algunos cambios, sin embargo, estaban llegando para tener gran influencia. En la Europa nórdica ciertos oscuros eruditos habían empezado thymidine phosphorylase inhibitor crear las bases de una ciencia fundamental para la burguesía moderna, la filología clásica, y sobre ella un neohumanismo fundamen
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br Possible reasons for the
2019-05-21
Possible reasons for the divergent results for the predictive value of PES for cardiac events First, there were methodological differences in the stimulation protocols used for PES, including the number of extrastimuli, the minimum coupling interval used (up to 200ms or refractoriness), the site
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